Endocrine Abstracts

Severe thyroid disorder are associated with important metabolic changes. After restoration of euthyroidism, as a result of proper treatment, usually body metabolism also normalizes. Up to date, there are conflicting reports about the changes in body composition of patients during treatment of severe hyperthyroidism and hypothyroidism. The aim of this study was to evaluate the body composition and glucose level changes in subjects affected by Graves disease and autoimmune thyro...

Introduction: Impaired insulin sensitivity accompanies polycystic ovary syndrome (PCOS). Women with PCOS are usually at risk of premature cardiovascular disease, which increases with age and body weight. We studied the link between insulin sensitivity measured by the Matsuda Insulin Sensitivity Index (MISI) adjusted to body mass index (BMI) and age in otherwise healthy PCOS women.Methods: 250 adult women with PCOS of reproductive age (18-43 years old) un...

Introduction: Polycystic ovary syndrome (PCOS) patients present with or without biochemical hyperandrogenism (HAPCOS or non-HAPCOS, respectively). Although cardiometabolic and hormonal abnormalities have been reported in women with PCOS, particularly those with hypertension, direct comparisons between normotensive (blood pressure (BP) <140/90 mmHg) patients with HAPCOS and non-HAPCOS are scarce. Data on N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) in PCO...